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http://purl.uniprot.org/citations/20231378http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20231378http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20231378http://www.w3.org/2000/01/rdf-schema#comment"Signals processed through the B cell antigen receptor (BCR) control both the proliferation and differentiation of B lymphocytes. How these different signaling modes are established at the BCR is poorly understood. We show that a conserved arginine in the tail sequence of the Igalpha subunit of the BCR is methylated by the protein arginine methyltransferase 1. This modification negatively regulates the calcium and PI-3 kinase pathways of the BCR while promoting signals leading to B cell differentiation. Thus, Igalpha arginine methylation can play an important role in specifying the outcome of BCR signaling."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.org/dc/terms/identifier"doi:10.1084/jem.20091303"xsd:string
http://purl.uniprot.org/citations/20231378http://purl.org/dc/terms/identifier"doi:10.1084/jem.20091303"xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Schneider R."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Schneider R."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Waldmann T."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Waldmann T."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Jung M."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Jung M."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Infantino S."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Infantino S."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Reth M."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Reth M."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Benz B."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/author"Benz B."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/name"J. Exp. Med."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/name"J. Exp. Med."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/pages"711-719"xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/pages"711-719"xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/title"Arginine methylation of the B cell antigen receptor promotes differentiation."xsd:string
http://purl.uniprot.org/citations/20231378http://purl.uniprot.org/core/title"Arginine methylation of the B cell antigen receptor promotes differentiation."xsd:string