| http://purl.uniprot.org/citations/2024466 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2024466 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2024466 | http://www.w3.org/2000/01/rdf-schema#comment | "To better understand the structure and function of a baculovirus regulatory gene, the nucleotide sequence of IE-N expressed by Autographa californica nuclear polyhedrosis virus was determined. The 2.0-kb PstI-EcoRV restriction fragment (97.5 to 98.9 mu) encodes the upstream regulatory sequences, open reading frame, and downstream sequences of the immediate early IE-N gene. Using a convenient restriction site, the 285-bp promoter of IE-N was divided into two functional regions as defined by transient expression assays of mutant sequences. The sequences of IE-N from -1 to -45 nt encoded a minimal promoter capable of directing low levels of transcription. The minimal promoter was fully responsive to positive regulation by IE-N. The upstream region from -46 to -285 nt contains two direct repeats which increased levels of IE-N gene expression. Computer-assisted translation of the IE-N sequence indicates that this fragment of DNA encodes a single long open reading frame with a predicted molecular weight of 47,000. The amino acid sequence of the predicted protein exhibits three motifs common to transcriptional regulators: a serine-threonine rich region, a proline-rich region, and a polyglutamine tract. IE-N autoregulates its own expression and stimulates both IE-1 and IE-0 in transient assays. The stimulation of IE-1 may account for the augmenting activity of IE-N in the IE-1-mediated trans-activation of the 39K promoter."xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.org/dc/terms/identifier | "doi:10.1016/0042-6822(91)90671-w"xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.org/dc/terms/identifier | "doi:10.1016/0042-6822(91)90671-w"xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/author | "Guarino L.A."xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/author | "Guarino L.A."xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/author | "Summers M.D."xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/author | "Summers M.D."xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/author | "Carson D.D."xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/author | "Carson D.D."xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/name | "Virology"xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/name | "Virology"xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/pages | "279-286"xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/pages | "279-286"xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/title | "Molecular analysis of a baculovirus regulatory gene."xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/title | "Molecular analysis of a baculovirus regulatory gene."xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/volume | "182"xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://purl.uniprot.org/core/volume | "182"xsd:string |
| http://purl.uniprot.org/citations/2024466 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2024466 |
| http://purl.uniprot.org/citations/2024466 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2024466 |
| http://purl.uniprot.org/citations/2024466 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2024466 |
| http://purl.uniprot.org/citations/2024466 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/2024466 |