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http://purl.uniprot.org/citations/20307606http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20307606http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20307606http://www.w3.org/2000/01/rdf-schema#comment"In our present work, seven conotoxins and conopeptides were cloned from four cone snail species based on the M-superfamily signal peptides. Among them, two conopeptides, Vt3.1 and Vt3.2, showed unusual sequence characteristics. Both of them contained two cysteines that are separated by just one non-cysteine residue. In vitro, the chemically synthesized Vt3.1 formed dimers with different intermolecular disulfide linkages. Only the dimer with crossed disulfides showed bioactivity when injected into the intraventricular region of mice brains. Therefore, Vt3.1 and Vt3.2 represent a new group of conopeptides that form disulfide-crosslinked dimers in vitro and probably in vivo."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.org/dc/terms/identifier"doi:10.1016/j.peptides.2010.03.010"xsd:string
http://purl.uniprot.org/citations/20307606http://purl.org/dc/terms/identifier"doi:10.1016/j.peptides.2010.03.010"xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Peng C."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Peng C."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Zhou M."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Zhou M."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Chi C.-W."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Chi C.-W."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Wu X.-C."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Wu X.-C."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Guo Z.-Y."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Guo Z.-Y."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Shao X.-X."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/author"Shao X.-X."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/name"Peptides"xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/name"Peptides"xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/pages"1001-1006"xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/pages"1001-1006"xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/title"Novel conopeptides in a form of disulfide-crosslinked dimer."xsd:string
http://purl.uniprot.org/citations/20307606http://purl.uniprot.org/core/title"Novel conopeptides in a form of disulfide-crosslinked dimer."xsd:string