DESCRIBE <http://purl.uniprot.org/citations/20339589>

Subject	Predicate	Object
http://purl.uniprot.org/citations/20339589	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20339589	http://www.w3.org/1999/02/22-rdf-syntax-ns#type	http://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20339589	http://www.w3.org/2000/01/rdf-schema#comment	" Background Cupriavidus necator JMP134 is a Gram-negative beta-proteobacterium able to grow on a variety of aromatic and chloroaromatic compounds as its sole carbon and energy source. Methodology/principal findings Its genome consists of four replicons (two chromosomes and two plasmids) containing a total of 6631 protein coding genes. Comparative analysis identified 1910 core genes common to the four genomes compared (C. necator JMP134, C. necator H16, C. metallidurans CH34, R. solanacearum GMI1000). Although secondary chromosomes found in the Cupriavidus, Ralstonia, and Burkholderia lineages are all derived from plasmids, analyses of the plasmid partition proteins located on those chromosomes indicate that different plasmids gave rise to the secondary chromosomes in each lineage. The C. necator JMP134 genome contains 300 genes putatively involved in the catabolism of aromatic compounds and encodes most of the central ring-cleavage pathways. This strain also shows additional metabolic capabilities towards alicyclic compounds and the potential for catabolism of almost all proteinogenic amino acids. This remarkable catabolic potential seems to be sustained by a high degree of genetic redundancy, most probably enabling this catabolically versatile bacterium with different levels of metabolic responses and alternative regulation necessary to cope with a challenging environment. From the comparison of Cupriavidus genomes, it is possible to state that a broad metabolic capability is a general trait for Cupriavidus genus, however certain specialization towards a nutritional niche (xenobiotics degradation, chemolithoautotrophy or symbiotic nitrogen fixation) seems to be shaped mostly by the acquisition of "specialized" plasmids. Conclusions/significance The availability of the complete genome sequence for C. necator JMP134 provides the groundwork for further elucidation of the mechanisms and regulation of chloroaromatic compound biodegradation."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.org/dc/terms/identifier	"doi:10.1371/journal.pone.0009729"xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.org/dc/terms/identifier	"doi:10.1371/journal.pone.0009729"xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Lapidus A."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Lapidus A."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Lucas S."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Lucas S."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Kyrpides N.C."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Kyrpides N.C."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Mavromatis K."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Mavromatis K."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Anderson I.J."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Anderson I.J."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Hooper S.D."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Hooper S.D."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Lykidis A."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Lykidis A."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Gonzalez B."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Gonzalez B."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Ivanova N.N."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Ivanova N.N."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Ledger T."xsd:string
http://purl.uniprot.org/citations/20339589	http://purl.uniprot.org/core/author	"Ledger T."xsd:string