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http://purl.uniprot.org/citations/20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20359089http://www.w3.org/2000/01/rdf-schema#comment"

Objective

To detect the expression of oncogene c-myc and explore its role on human laryngeal cancer.

Method

The mRNA and of oncogene c-myc levels were detected in human laryngeal cancer tissues and laryngeal normal tissues by the means of real-time PCR and immunohistochemistry, respectively.

Result

Compared with normal laryngeal tissues, the mRNA and protein levels of oncogene c-myc were both upregulated in laryngeal cancer tissues of all differentiation degree (P<0.05). Moreover, the level of c-myc was inverse correlated with the differentiation degree in human laryngeal cancer tissues.

Conclusion

The oncogene c-myc is overexpressed in human laryngeal cancer tissues, and c-myc may play an important role in carcinogenesis and progression of human laryngeal cancer tissues. It may provide a new target for gene therapy of human laryngeal cancer."xsd:string
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/author"Hu S."xsd:string
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/author"Liu Z."xsd:string
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/author"Long X."xsd:string
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/author"Cao P."xsd:string
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/author"Cui Y."xsd:string
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/author"Zhen H."xsd:string
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/name"Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"xsd:string
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/pages"1127-1129"xsd:string
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/title"[The expression of oncogene c-myc and its role on human laryngeal cancer]."xsd:string
http://purl.uniprot.org/citations/20359089http://purl.uniprot.org/core/volume"23"xsd:string
http://purl.uniprot.org/citations/20359089http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20359089
http://purl.uniprot.org/citations/20359089http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20359089
http://purl.uniprot.org/uniprot/#_A0A0B4J1R1-mappedCitation-20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20359089
http://purl.uniprot.org/uniprot/#_A0N2G3-mappedCitation-20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20359089
http://purl.uniprot.org/uniprot/#_A0A224B085-mappedCitation-20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20359089
http://purl.uniprot.org/uniprot/#_B3CJ86-mappedCitation-20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20359089
http://purl.uniprot.org/uniprot/#_B3CJ87-mappedCitation-20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20359089
http://purl.uniprot.org/uniprot/#_B3CJ88-mappedCitation-20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20359089
http://purl.uniprot.org/uniprot/#_B3CJB3-mappedCitation-20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20359089
http://purl.uniprot.org/uniprot/#_B3CJB8-mappedCitation-20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20359089
http://purl.uniprot.org/uniprot/#_B3CJ63-mappedCitation-20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20359089
http://purl.uniprot.org/uniprot/#_B3CJ64-mappedCitation-20359089http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20359089
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