| http://purl.uniprot.org/citations/20360743 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20360743 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20360743 | http://www.w3.org/2000/01/rdf-schema#comment | "Jasmonoyl-isoleucine (JA-Ile) is a plant hormone that regulates a broad array of plant defence and developmental processes. JA-Ile-responsive gene expression is regulated by the transcriptional activator MYC2 that interacts physically with the jasmonate ZIM-domain (JAZ) repressor proteins. On perception of JA-Ile, JAZ proteins are degraded and JA-Ile-dependent gene expression is activated. The molecular mechanisms by which JAZ proteins repress gene expression remain unknown. Here we show that the Arabidopsis JAZ proteins recruit the Groucho/Tup1-type co-repressor TOPLESS (TPL) and TPL-related proteins (TPRs) through a previously uncharacterized adaptor protein, designated Novel Interactor of JAZ (NINJA). NINJA acts as a transcriptional repressor whose activity is mediated by a functional TPL-binding EAR repression motif. Accordingly, both NINJA and TPL proteins function as negative regulators of jasmonate responses. Our results point to TPL proteins as general co-repressors that affect multiple signalling pathways through the interaction with specific adaptor proteins. This new insight reveals how stress-related and growth-related signalling cascades use common molecular mechanisms to regulate gene expression in plants."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature08854"xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.org/dc/terms/identifier | "doi:10.1038/nature08854"xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "De Jaeger G."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "De Jaeger G."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Goossens A."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Goossens A."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Inze D."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Inze D."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Solano R."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Solano R."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Grunewald W."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Grunewald W."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Long J.A."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Long J.A."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Pauwels L."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Pauwels L."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Sewell J."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Sewell J."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Tilleman S."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Tilleman S."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Gil E."xsd:string |
| http://purl.uniprot.org/citations/20360743 | http://purl.uniprot.org/core/author | "Gil E."xsd:string |