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http://purl.uniprot.org/citations/20378371http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20378371http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20378371http://www.w3.org/2000/01/rdf-schema#comment"Ets-1 is a transcription factor that is highly expressed within lymphoid cells, where it is known to control their differentiation, survival and proliferation. Ets-1 is also expressed in other cell types and can be further induced by a variety of stimuli. Accumulating evidence points to an important role for Ets-1 in regulating the differentiation of T helper cell subsets, cytotoxic T cells, B cells and other cell types. Ets-1 also directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. In this review, we summarize the known roles for Ets-1 in regulating the differentiation of immune cells and other cell types. Furthermore, we review in detail the current understanding of Ets-1 regulation of cytokine and chemokine expression and how this may relate to the biological roles of Ets-1 in regulating immunity as well as in cancer progression."xsd:string
http://purl.uniprot.org/citations/20378371http://purl.org/dc/terms/identifier"doi:10.1016/j.cyto.2010.03.006"xsd:string
http://purl.uniprot.org/citations/20378371http://purl.org/dc/terms/identifier"doi:10.1016/j.cyto.2010.03.006"xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/author"Russell L."xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/author"Russell L."xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/author"Garrett-Sinha L.A."xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/author"Garrett-Sinha L.A."xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/name"Cytokine"xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/name"Cytokine"xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/pages"217-226"xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/pages"217-226"xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/title"Transcription factor Ets-1 in cytokine and chemokine gene regulation."xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/title"Transcription factor Ets-1 in cytokine and chemokine gene regulation."xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/volume"51"xsd:string
http://purl.uniprot.org/citations/20378371http://purl.uniprot.org/core/volume"51"xsd:string
http://purl.uniprot.org/citations/20378371http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20378371
http://purl.uniprot.org/citations/20378371http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20378371
http://purl.uniprot.org/citations/20378371http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20378371
http://purl.uniprot.org/citations/20378371http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20378371
http://purl.uniprot.org/uniprot/P14921http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/20378371
http://purl.uniprot.org/uniprot/P14921#attribution-4C9E93180755CC3CD8A8CA86B84A2363http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/20378371