| http://purl.uniprot.org/citations/20380521 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20380521 | http://www.w3.org/2000/01/rdf-schema#comment | "The etiology of Systemic lupus erythematosus (SLE) seems to be multifactorial including environmental as well as genetic factors. Major histocompatibility complex (MHC) genes especially HLA-DRB1 and HLA-DQB1 are strongly implicated in susceptibility to SLE. Moreover ethnicity has been found to have a significant role in both disease susceptibility and disease expression. This study was carried out to determine HLA-DRB1 allele association with SLE susceptibility and disease presentation in Egyptian children with juvenile onset SLE. HLA-DRB1 allele typing was done using polymerase chain reaction-sequence-specific oligonucleotide probe for 65 juvenile Egyptian SLE patients and 150 healthy controls. p-values were corrected for the number of the alleles tested (Pc). HLA-DRB1*15 g allele was significantly increased in SLE children versus controls (OR = 4.76; 95% CI = 1.83-12.4; p = 0.001 and Pc = 0.012). No HLA-DRB1 allele was found to be statistically significant associated with musculoskeletal, cutaneous, hematologic, cardiac or neuropsychiatric manifestations in SLE patients (p > 0.05). Moreover no statistically significant association was found between HLA-DRB1 alleles and clinical presentation or histologic classes of lupus nephritis. The current work suggests that HLA-DRB1*15g allele may be a susceptibility allele in Egyptian children with SLE but is not related to clinical presentation of SLE."xsd:string |
| http://purl.uniprot.org/citations/20380521 | http://purl.org/dc/terms/identifier | "doi:10.3109/08820131003615480"xsd:string |
| http://purl.uniprot.org/citations/20380521 | http://purl.uniprot.org/core/author | "Hammad A."xsd:string |
| http://purl.uniprot.org/citations/20380521 | http://purl.uniprot.org/core/author | "Youssef H.M."xsd:string |
| http://purl.uniprot.org/citations/20380521 | http://purl.uniprot.org/core/author | "Mosaad Y.M."xsd:string |
| http://purl.uniprot.org/citations/20380521 | http://purl.uniprot.org/core/author | "Elhanbly S."xsd:string |
| http://purl.uniprot.org/citations/20380521 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20380521 | http://purl.uniprot.org/core/name | "Immunol Invest"xsd:string |
| http://purl.uniprot.org/citations/20380521 | http://purl.uniprot.org/core/pages | "235-244"xsd:string |
| http://purl.uniprot.org/citations/20380521 | http://purl.uniprot.org/core/title | "HLA-DRB1*15 confers susceptibility to juvenile SLE but is not associated with disease presentation: an Egyptian Study."xsd:string |
| http://purl.uniprot.org/citations/20380521 | http://purl.uniprot.org/core/volume | "39"xsd:string |
| http://purl.uniprot.org/citations/20380521 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20380521 |
| http://purl.uniprot.org/citations/20380521 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20380521 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-20380521 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20380521 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-20380521 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20380521 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-20380521 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20380521 |
| http://purl.uniprot.org/uniprot/#_A0A0A0WDZ3-mappedCitation-20380521 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20380521 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DD60-mappedCitation-20380521 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20380521 |
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| http://purl.uniprot.org/uniprot/#_A0A141AZI3-mappedCitation-20380521 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20380521 |
| http://purl.uniprot.org/uniprot/#_A0A141AZI4-mappedCitation-20380521 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20380521 |
| http://purl.uniprot.org/uniprot/#_A0A0A0WAE5-mappedCitation-20380521 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20380521 |
| http://purl.uniprot.org/uniprot/#_A0A0A0WB88-mappedCitation-20380521 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20380521 |