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http://purl.uniprot.org/citations/20385791http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20385791http://www.w3.org/2000/01/rdf-schema#comment"Genome-wide association and candidate gene studies implicate different genetic variants within the 6p21 chromosomal region with different non-Hodgkin lymphoma (NHL) subtypes. Complementing these efforts, we conducted human leukocyte antigen (HLA) class I and class II genotyping among 610 NHL cases and 555 controls of non-Hispanic white descent from a US multicenter study. Allele-disease associations were assessed by logistic regression for NHL and its subtypes. Statistically significant associations between HLA and NHL subtypes include HLA-DRB1*0101 for follicular lymphoma (odds ratio [OR] = 2.14, P < .001), HLA-DRB1*0401 for diffuse large B-cell lymphoma (DLBCL; OR = 0.45, P = .006), and HLA-DRB1*13 and follicular lymphoma (OR = 0.48, P = .008). We further observed significant heterozygote advantage for HLA class I alleles and NHL, and particularly DLBCL (P trend = .01 for elevated risk with increasing number of homozygous alleles). Our results support a role for HLA in the etiology of NHL and its subtypes."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.org/dc/terms/identifier"doi:10.1182/blood-2010-01-266775"xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Carrington M."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Gao X."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Wang S.S."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Thomas R."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Davis S."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Hartge P."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Bernstein L."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Cozen W."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Cerhan J.R."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Rothman N."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Severson R.K."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Morton L.M."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/author"Abdou A.M."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/name"Blood"xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/pages"4820-4823"xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/title"Human leukocyte antigen class I and II alleles in non-Hodgkin lymphoma etiology."xsd:string
http://purl.uniprot.org/citations/20385791http://purl.uniprot.org/core/volume"115"xsd:string
http://purl.uniprot.org/citations/20385791http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20385791
http://purl.uniprot.org/citations/20385791http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20385791
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-20385791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20385791
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-20385791http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20385791