http://purl.uniprot.org/citations/20391533 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20391533 | http://www.w3.org/2000/01/rdf-schema#comment | "MIP-T3 (microtubule-interacting protein associated with TRAF3) is a microtubule-interacting protein that evolutionarily conserved from worms to humans, but whose cellular functions remains unknown. To get insight into the functions of MIP-T3, we set out to identify MIP-T3 interacting proteins by immunoprecipitation in human embryonic kidney 293 cells and MS analysis. As the results, a total of 34 proteins were identified and most of them were novel MIP-T3 putative partners. The MIP-T3-associated proteins could be grouped into nine clusters based on their molecule functions, including cytoskeleton, chaperone, nucleic acid binding, kinase and so on. Three MIP-T3-interacted proteins - actin, HSPA8 and tubulin - were further confirmed by reciprocal coimmunoprecipitations and colocalization analysis. The interaction of MIP-T3 with both actin filaments and microtubule suggested that MIP-T3 may play an important role in regulation of cytoskeleton dynamics in cells. Our results therefore not only uncover a large number of MIP-T3-associated proteins that possess a variety of cellular functions, but also provide new research directions for the study of the functions of MIP-T3."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.org/dc/terms/identifier | "doi:10.1002/pmic.201000130"xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/author | "Liu G."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/author | "Wang Y.F."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/author | "Zhang X.E."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/author | "Ge F."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/author | "Zhang Z.P."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/author | "Xiong S."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/author | "Kitazato K."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/author | "He Q.Y."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/author | "Guo C.W."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/name | "Proteomics"xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/pages | "2337-2347"xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/title | "Proteomic analysis reveals novel binding partners of MIP-T3 in human cells."xsd:string |
http://purl.uniprot.org/citations/20391533 | http://purl.uniprot.org/core/volume | "10"xsd:string |
http://purl.uniprot.org/citations/20391533 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20391533 |
http://purl.uniprot.org/citations/20391533 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20391533 |
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