| http://purl.uniprot.org/citations/20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20406616 | http://www.w3.org/2000/01/rdf-schema#comment | "ObjectivesTo determine the prevalence and clinical characteristics of ankylosing spondylitis (AS) in the Icelandic population, which carries a high prevalence of HLA-B27.MethodsA nationwide search was performed by screening hospital records and private rheumatology services for cases of AS in association with an on-going genetic study. Individuals diagnosed with AS according to the modified New York criteria were asked to participate in the study by answering a standardised questionnaire and to undergo an interview and clinical evaluation.ResultsA total of 256 individuals fulfilled the modified New York classification criteria for AS (169 male, 87 female); 84% of these individuals were HLA-B27 positive vs. 15% in the population (p<10-16). Of those contacted 223 patients (87.1%) answered the standardised questionnaire and were included in the study. The prevalence of AS in Iceland was 0.13% (CI 0.11-0.14%). A highly conservative prevalence number, based only on clinically evaluated patients, gave prevalence of 0.10% (CI 0.09-0.11%). Mean age at onset of symptoms was 24+/-8 years and at diagnosis 32.1+/-10.2 for male and 34.2+/-10.1 for female patients (not significant). Female patients more often had arthritis in peripheral joints and male patients were more often diagnosed with iritis. Prostatitis was experienced by 27% of male patients.ConclusionsAS is less common in the Icelandic population than reported in various Caucasian populations with a similar prevalence of HLA-B27."xsd:string |
| http://purl.uniprot.org/citations/20406616 | http://purl.uniprot.org/core/author | "Bjornsdottir G."xsd:string |
| http://purl.uniprot.org/citations/20406616 | http://purl.uniprot.org/core/author | "Kristjansson K."xsd:string |
| http://purl.uniprot.org/citations/20406616 | http://purl.uniprot.org/core/author | "Eyjolfsdottir H."xsd:string |
| http://purl.uniprot.org/citations/20406616 | http://purl.uniprot.org/core/author | "Geirsson A.J."xsd:string |
| http://purl.uniprot.org/citations/20406616 | http://purl.uniprot.org/core/author | "Gudbjornsson B."xsd:string |
| http://purl.uniprot.org/citations/20406616 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20406616 | http://purl.uniprot.org/core/name | "Clin Exp Rheumatol"xsd:string |
| http://purl.uniprot.org/citations/20406616 | http://purl.uniprot.org/core/pages | "333-340"xsd:string |
| http://purl.uniprot.org/citations/20406616 | http://purl.uniprot.org/core/title | "Prevalence and clinical characteristics of ankylosing spondylitis in Iceland - a nationwide study."xsd:string |
| http://purl.uniprot.org/citations/20406616 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/20406616 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20406616 |
| http://purl.uniprot.org/citations/20406616 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC98-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DCA1-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A068B107-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A068B112-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A068B116-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A068B2J5-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A068B2Z1-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A068B6T8-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |
| http://purl.uniprot.org/uniprot/#_A0A089PAU6-mappedCitation-20406616 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20406616 |