| http://purl.uniprot.org/citations/20430450 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20430450 | http://www.w3.org/2000/01/rdf-schema#comment | "A recent meta-analysis of genome-wide association screens coupled to a replication exercise in a combined US/UK collection led to the identification of 4 single nucleotide polymorphisms (SNPs) in three gene loci, i.e. TNFRSF1A, CD6 and IRF8, as novel risk factors for multiple sclerosis with genome-wide level of significance. In the present study, using a combined all-Spain collection of 2515 MS patients and 2942 healthy controls, we demonstrate significant association of rs17824933 in CD6 (P(CMH)=0.004; OR=1.14; 95% CI 1.04-1.24) and of rs1860545 in TNFRSF1A (P(CMH)=0.001; OR=1.15; 95% CI 1.06-1.25) with MS, while the low-frequency coding non-synonymous SNP rs4149584 in TNFRSF1A displayed a trend for association (P(CMH)=0.062; OR=1.27; 95% CI 0.99-1.63). This data reinforce a generic role for CD6 and TNFRSF1A in susceptibility to MS, extending to populations of southern European ancestry."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jneuroim.2010.03.020"xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Swaminathan B."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Alcina A."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Matesanz F."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Arroyo R."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Otaegui D."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Urcelay E."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Vandenbroeck K."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Fernandez O."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Barcina M.G."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "de las Heras V."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Olascoaga J."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Alloza I."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Antiguedad A."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Cenit M.C."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/author | "Cavanillas M.L."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/name | "J Neuroimmunol"xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/pages | "100-103"xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/title | "Validation of the CD6 and TNFRSF1A loci as risk factors for multiple sclerosis in Spain."xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://purl.uniprot.org/core/volume | "223"xsd:string |
| http://purl.uniprot.org/citations/20430450 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20430450 |
| http://purl.uniprot.org/citations/20430450 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20430450 |