| http://purl.uniprot.org/citations/20443655 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20443655 | http://www.w3.org/2000/01/rdf-schema#comment | "Stimulation of beta1- and beta2-adrenergic receptors (ARs) in the heart results in positive inotropy. In contrast, it has been reported that the beta3-AR is also expressed in the heart and that its stimulation leads to negative inotropic effects. The aim of this study was to investigate the expression of beta3-AR in age-related heart-failure rats and its relevance to left ventricular dysfunction. Aging male Wistar rats were divided into young and aging groups according to age, and each group included sham-operation and heart-failure subgroups. Left ventricular end-diastolic pressure (LVEDP) and the ratio of left ventricular weight to body weight (LV/BW) were significantly higher for the aging heart-failure versus young heart-failure and the heart-failure versus sham-operation groups (P < 0.01, respectively). However, the left ventricular end-systolic pressure (LVESP) and the maximal rate of rise or fall of left ventricular pressure were all significantly lower for the aging heart-failure versus young heart-failure and the heart-failure versus sham-operation groups (P < 0.01, respectively). beta3-AR protein levels increased significantly when heart failure worsened in aging rats. These results suggest that beta3-AR expression in age-related heart-failure rats and left ventricular function were highly correlated."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.org/dc/terms/identifier | "doi:10.3109/10799891003801918"xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/author | "Chen Z."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/author | "Liu M."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/author | "Lu L."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/author | "Miao G."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/author | "Zhang Z."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/author | "Zhang L."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/author | "Fang X."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/author | "Hao G."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/name | "J Recept Signal Transduct Res"xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/pages | "227-233"xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/title | "Age-related up-regulation of beta3-adrenergic receptor in heart-failure rats."xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://purl.uniprot.org/core/volume | "30"xsd:string |
| http://purl.uniprot.org/citations/20443655 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20443655 |
| http://purl.uniprot.org/citations/20443655 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20443655 |
| http://purl.uniprot.org/uniprot/#_A6IVX2-mappedCitation-20443655 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20443655 |
| http://purl.uniprot.org/uniprot/#_A6IVX3-mappedCitation-20443655 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20443655 |
| http://purl.uniprot.org/uniprot/#_P26255-mappedCitation-20443655 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20443655 |
| http://purl.uniprot.org/uniprot/P26255 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/20443655 |
| http://purl.uniprot.org/uniprot/A6IVX2 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/20443655 |