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| http://purl.uniprot.org/citations/20445238 | http://www.w3.org/2000/01/rdf-schema#comment | "The crystal structure of human carbonic anhydrase II with a doubled a axis from that of the usually observed monoclinic unit cell has been determined and refined to 1.4 A resolution. The diffraction data with h = 2n + 1 were systematically weaker than those with h = 2n. Consequently, the scaling of the data, structure solution and refinement were challenging. The two molecules comprising the asymmetric unit are related by a noncrystallographic translation of (1/2) along a, but one of the molecules has two alternate positions related by a rotation of approximately 2 degrees. This rotation axis is located near the edge of the central beta-sheet, causing a maximum distance disparity of 1.7 A between equivalent atoms on the diametrically opposite side of the molecule. The crystal-packing contacts are similar to two sequential combined unit cells along a of the previously determined monoclinic unit cell. Abnormally high final R(cryst) and R(free) values (20.2% and 23.7%, respectively) are not unusual for structures containing pseudo-translational symmetry and probably result from poor signal to noise in the weak h-odd data."xsd:string |
| http://purl.uniprot.org/citations/20445238 | http://purl.org/dc/terms/identifier | "doi:10.1107/s0907444910006797"xsd:string |
| http://purl.uniprot.org/citations/20445238 | http://purl.uniprot.org/core/author | "Agbandje-McKenna M."xsd:string |
| http://purl.uniprot.org/citations/20445238 | http://purl.uniprot.org/core/author | "McKenna R."xsd:string |
| http://purl.uniprot.org/citations/20445238 | http://purl.uniprot.org/core/author | "Robbins A.H."xsd:string |
| http://purl.uniprot.org/citations/20445238 | http://purl.uniprot.org/core/author | "Domsic J.F."xsd:string |
| http://purl.uniprot.org/citations/20445238 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20445238 | http://purl.uniprot.org/core/name | "Acta Crystallogr D Biol Crystallogr"xsd:string |
| http://purl.uniprot.org/citations/20445238 | http://purl.uniprot.org/core/pages | "628-634"xsd:string |
| http://purl.uniprot.org/citations/20445238 | http://purl.uniprot.org/core/title | "Structure of a monoclinic polymorph of human carbonic anhydrase II with a doubled a axis."xsd:string |
| http://purl.uniprot.org/citations/20445238 | http://purl.uniprot.org/core/volume | "66"xsd:string |
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