| http://purl.uniprot.org/citations/20445263 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20445263 | http://www.w3.org/2000/01/rdf-schema#comment | "6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase (HPPK) catalyzes the Mg(2+)-dependent transfer of pyrophosphate from ATP to 6-hydroxymethyl-7,8-dihydropterin (HMDP), forming 6-hydroxymethyl-7,8-dihydropterin pyrophosphate, which is a critical step in the de novo folic acid-biosynthesis pathway. Diffraction-quality crystals of HPPK from the medically relevant species Staphylococcus aureus were grown in the presence of ammonium sulfate or sodium malonate and diffracted to better than 1.65 A resolution. The crystals belonged to space group P2(1), with unit-cell parameters a = 36.8, b = 76.6, c = 51.5 A, alpha = gamma = 90.0, beta = 100.2 degrees . The crystals contained two molecules per asymmetric unit, with a volume per protein weight (V(M)) of 2.04 A(3) Da(-1) and an estimated solvent content of 39.6%."xsd:string |
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| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/author | "Newman J."xsd:string |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/author | "Peat T.S."xsd:string |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/author | "Fernley R.T."xsd:string |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/author | "Swarbrick J.D."xsd:string |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/author | "Chhabra S."xsd:string |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/author | "Caine J."xsd:string |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/author | "Simpson J.S."xsd:string |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/name | "Acta Crystallogr Sect F Struct Biol Cryst Commun"xsd:string |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/pages | "575-578"xsd:string |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/title | "Crystallization and preliminary X-ray analysis of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus."xsd:string |
| http://purl.uniprot.org/citations/20445263 | http://purl.uniprot.org/core/volume | "66"xsd:string |
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