http://purl.uniprot.org/citations/20447398 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20447398 | http://www.w3.org/2000/01/rdf-schema#comment | "Recent evidence suggests that non-muscle myosin IIB (NMIIB) contributes to smooth muscle contraction. This study was designed to determine the effects of NMIIB on the cross-bridge cycling rate. The cross-bridge cycling rate was investigated using sinusoidal analysis. Frequency analysis revealed two asymptotes in the Bode plot of the data; and the intersection of the asymptotes (corner frequency) was higher for the B(+/-) strain (8.73+/-1.10 Hz vs 16.56+/-1.26 Hz, P<0.05), consistent with a higher overall cross-bridge cycling rate in heterozygous NMIIB KO (B(+/-)) vs WT mice. These results demonstrate that because of their long duty cycle, NMIIB cross-bridges act as an internal load on smooth muscle myosin to decrease the overall cross-bridge cycling rate and muscle V(max) during force maintenance."xsd:string |
http://purl.uniprot.org/citations/20447398 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2010.04.070"xsd:string |
http://purl.uniprot.org/citations/20447398 | http://purl.uniprot.org/core/author | "Ozturk N."xsd:string |
http://purl.uniprot.org/citations/20447398 | http://purl.uniprot.org/core/author | "Brozovich F.V."xsd:string |
http://purl.uniprot.org/citations/20447398 | http://purl.uniprot.org/core/author | "Guvenc B."xsd:string |
http://purl.uniprot.org/citations/20447398 | http://purl.uniprot.org/core/author | "Ustunel C."xsd:string |
http://purl.uniprot.org/citations/20447398 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20447398 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/20447398 | http://purl.uniprot.org/core/pages | "2862-2866"xsd:string |
http://purl.uniprot.org/citations/20447398 | http://purl.uniprot.org/core/title | "A dynamic approach reveals non-muscle myosin influences the overall smooth muscle cross-bridge cycling rate."xsd:string |
http://purl.uniprot.org/citations/20447398 | http://purl.uniprot.org/core/volume | "584"xsd:string |
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