| http://purl.uniprot.org/citations/20448247 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20448247 | http://www.w3.org/2000/01/rdf-schema#comment | "Important factors involved in odontogenesis in mouse dental papillae disappear between the pre- and post-natal stages of development. Therefore, we hypothesized that certain genes involved in odontogenesis in dental papillae were subject to pre-/post-natal down-regulation. Our goal was to identify, by microarray analysis, which genes were down-regulated. Dental papillae were isolated from embryonic 16-day-, 18-day-(E16, E18), and post-natal 3-day-old (P3) murine first mandibular molar germs and analyzed by microarray. The number of down-regulated genes was 2269 between E16 and E18, and 3130 between E18 and P3. Drastic down-regulation (fold change > 10.0) of Adamts4, Aldha1a2, and Lef1 was observed at both E16 and E18, and quantitative RT-PCR revealed a post-natal reduction in their expression (Adamts4, 1/3; Aldh1a2, 1/13; and Lef1, 1/37). These results suggest that down-regulation of these three genes is an important factor in normal odontogenesis in dental papillae."xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.org/dc/terms/identifier | "doi:10.1177/0022034510366844"xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/author | "Hashimoto S."xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/author | "Yamamoto H."xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/author | "Muramatsu T."xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/author | "Sasaki H."xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/author | "Shimono M."xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/author | "Kwon H.J."xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/author | "Jung H.S."xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/name | "J Dent Res"xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/pages | "679-683"xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/title | "Down-regulated genes in mouse dental papillae and pulp."xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://purl.uniprot.org/core/volume | "89"xsd:string |
| http://purl.uniprot.org/citations/20448247 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20448247 |
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| http://purl.uniprot.org/uniprot/#_P27782-mappedCitation-20448247 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20448247 |
| http://purl.uniprot.org/uniprot/#_Q3TEN5-mappedCitation-20448247 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20448247 |