| http://purl.uniprot.org/citations/2044959 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2044959 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/2044959 | http://www.w3.org/2000/01/rdf-schema#comment | "The retroviral integration site Fli-1 is rearranged in 75% of the erythroleukemia cell clones induced by Friend murine leukemia virus (F-MuLV), whereas Spi-1/PU.1, a member of the ets family of DNA-binding proteins, is rearranged in 95% of the erythroleukemias induced by Friend spleen focus-forming virus (SFFV). To determine the transcriptional domain defined by Fli-1, we have isolated a cDNA clone that is highly expressed only in erythroleukemia cell lines with Fli-1 rearrangements. The protein sequence of this cDNA is very similar to Erg2, another member of the ets gene family. The hydrophilic carboxy-terminal end of the Fli-1 cDNA shares significant sequence similarity to the DNA-binding ETS domain found in all members of the ets family. PFGE analysis localized Fli-1 within 240 kb of the ets-1 proto-oncogene on mouse chromosome 9 and human chromosome 11q23, suggesting that ets-1 and Fli-1 arose from a common ancestral gene by gene duplication. The involvement of the murine Fli-1, Spi-1, and avian v-ets genes in erythroleukemia induction suggests that activation of ets gene family members plays an important role in the progression of these multistage malignancies."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.5.6.908"xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.5.6.908"xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/author | "Bernstein A."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/author | "Bernstein A."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/author | "Ben-David Y."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/author | "Ben-David Y."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/author | "Letwin K."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/author | "Letwin K."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/author | "Giddens E.B."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/author | "Giddens E.B."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/name | "Genes Dev."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/pages | "908-918"xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/pages | "908-918"xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/title | "Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/title | "Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1."xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://purl.uniprot.org/core/volume | "5"xsd:string |
| http://purl.uniprot.org/citations/2044959 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2044959 |
| http://purl.uniprot.org/citations/2044959 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/2044959 |