http://purl.uniprot.org/citations/20460642 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20460642 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20460642 | http://www.w3.org/2000/01/rdf-schema#comment | "Although childhood acute lymphoblastic leukemia is the most common pediatric cancer, its etiology remains poorly understood. In an attempt to replicate the findings of 2 recent genome-wide association studies in a French-Canadian cohort, we confirmed the association of 5 SNPs [rs7073837 (P=4.2 x 10(-4)), rs10994982 (P=3.8 x 10(-4)), rs10740055 (P=1.6 x 10(-5)), rs10821936 (P=1.7 x 10(-7)) and rs7089424 (P=3.6 x 10(-7))] in the ARID5B gene with childhood acute lymphoblastic leukemia. We also confirmed a selective effect for B-cell acute lymphoblastic leukemia with hyperdiploidy and report a putative gender-specific effect of ARID5B SNPs on acute lymphoblastic leukemia risk in males. This study provides a strong rationale for more detailed analysis to identify the causal variants at this locus and to better understand the overall functional contribution of ARID5B to childhood acute lymphoblastic leukemia susceptibility."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.org/dc/terms/identifier | "doi:10.3324/haematol.2010.022459"xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.org/dc/terms/identifier | "doi:10.3324/haematol.2010.022459"xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/author | "Bourgey M."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/author | "Bourgey M."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/author | "Healy J."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/author | "Healy J."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/author | "Kritikou E.A."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/author | "Kritikou E.A."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/author | "Richer C."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/author | "Richer C."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/author | "Sinnett D."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/author | "Sinnett D."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/name | "Haematologica"xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/name | "Haematologica"xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/pages | "1608-1611"xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/pages | "1608-1611"xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/title | "Replication analysis confirms the association of ARID5B with childhood B-cell acute lymphoblastic leukemia."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/title | "Replication analysis confirms the association of ARID5B with childhood B-cell acute lymphoblastic leukemia."xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/volume | "95"xsd:string |
http://purl.uniprot.org/citations/20460642 | http://purl.uniprot.org/core/volume | "95"xsd:string |