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http://purl.uniprot.org/citations/20466003http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20466003http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20466003http://www.w3.org/2000/01/rdf-schema#comment"Adenylyl cyclase (AC) type VI (AC6) is a calcium-inhibitable enzyme which produces cAMP upon stimulation. Herein, we characterized the specific role of AC6 in the kidneys using two AC6-knockout mouse lines. Immunohistochemical staining revealed that AC6 exists in the tubular parts of the nephron and collecting duct. Activities of AC evoked by forskolin or a selective agonist of the V2 vasopressin receptor were lower in the kidneys of AC6-null mice compared to those of wildtype mice. Results of a metabolic cage assay and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) showed for the first time that AC6 plays a critical role in regulating water homeostasis."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2010.05.004"xsd:string
http://purl.uniprot.org/citations/20466003http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2010.05.004"xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Chen Y.H."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Chen Y.H."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Chang C."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Chang C."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Lin S.S."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Lin S.S."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Chern Y."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Chern Y."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Lai H.L."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Lai H.L."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Wu Y.S."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Wu Y.S."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Chien C.L."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Chien C.L."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Jiang S.T."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Jiang S.T."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Shih C.M."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/author"Shih C.M."xsd:string
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20466003http://purl.uniprot.org/core/date"2010"xsd:gYear