| http://purl.uniprot.org/citations/20471636 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20471636 | http://www.w3.org/2000/01/rdf-schema#comment | "p73, a recently described member of the p53 family of transcription factors, undergoes a number of posttranslational modifications, inducing cell cycle arrest and apoptosis. In the present study, we demonstrate that PIASy, a member of the PIAS SUMO-ligase family, interacts with p73alpha, and that PIASy-mediated sumoylation promotes proteasomal degradation of p73alpha. PIASy overexpression inhibits p73alpha-mediated transcription of p21, with a reduction of cells in G1 and cell cycle reentry. These results suggest that PIASy plays an important role in regulation of p73alpha transcriptional activity and is also a regulator of the cell cycle machinery."xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cellimm.2010.04.005"xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/author | "Luo L."xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/author | "Zhang C."xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/author | "Yuan X."xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/author | "Yin Z."xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/author | "Fu J."xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/author | "Yue L."xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/name | "Cell Immunol"xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/pages | "235-240"xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/title | "PIASy interacts with p73alpha and regulates cell cycle in HEK293 cells."xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://purl.uniprot.org/core/volume | "263"xsd:string |
| http://purl.uniprot.org/citations/20471636 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20471636 |
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