http://purl.uniprot.org/citations/20486243 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20486243 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20486243 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
http://purl.uniprot.org/citations/20486243 | http://www.w3.org/2000/01/rdf-schema#comment | "The solanapyrone biosynthetic gene cluster was cloned from Alternaria solani. It consists of six genes-sol1-6-coding for a polyketide synthase, an O-methyltransferase, a dehydrogenase, a transcription factor, a flavin-dependent oxidase, and cytochrome P450. The prosolanapyrone synthase (PSS) encoded by sol1 was expressed in Aspergillus oryzae and its product was identified as desmethylprosolanapyrone I (8). Although PSS is closely related to the PKSs/Diels-Alderases LovB and MlcA of lovastatin and compactin biosynthesis, it did not catalyze cycloaddition. Sol5, encoding a flavin-dependent oxidase (solanapyrone synthase, SPS), was expressed in Pichia pastoris and purified. The purified recombinant SPS showed activity for the formation of (-)-solanapyrone A (1) from achiral prosolanapyrone II (2), establishing that this single enzyme catalyzes both the oxidation and the subsequent cycloaddition reaction, possibly as a Diels-Alder enzyme."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.org/dc/terms/identifier | "doi:10.1002/cbic.201000173"xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.org/dc/terms/identifier | "doi:10.1002/cbic.201000173"xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Miyamoto T."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Miyamoto T."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Ebizuka Y."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Ebizuka Y."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Oikawa H."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Oikawa H."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Fujimoto T."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Fujimoto T."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Fujii I."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Fujii I."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Kasahara K."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Kasahara K."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Oguri H."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Oguri H."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Tokiwano T."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/author | "Tokiwano T."xsd:string |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20486243 | http://purl.uniprot.org/core/name | "ChemBioChem"xsd:string |