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http://purl.uniprot.org/citations/20493689http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20493689http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20493689http://www.w3.org/2000/01/rdf-schema#comment"We have designed and synthesized a novel series of alpha-amino cyclic boronates and incorporated them successfully in several acyclic templates at the P1 position. These compounds are inhibitors of the HCV NS3 serine protease, and structural studies show that they inhibit the NS3 protease by trapping the Ser-139 hydroxyl group in the active site. Synthetic methodologies and SARs of this series of compounds are described."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.org/dc/terms/identifier"doi:10.1016/j.bmcl.2010.04.129"xsd:string
http://purl.uniprot.org/citations/20493689http://purl.org/dc/terms/identifier"doi:10.1016/j.bmcl.2010.04.129"xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Fan D."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Fan D."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Liu Y."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Liu Y."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Li X."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Li X."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Li Q."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Li Q."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Qian X."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Qian X."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Zhou Y."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Zhou Y."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Zou W."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Zou W."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Zhang Y.K."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Zhang Y.K."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Liao L."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Liao L."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Baker S.J."xsd:string
http://purl.uniprot.org/citations/20493689http://purl.uniprot.org/core/author"Baker S.J."xsd:string