| http://purl.uniprot.org/citations/20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20507388 | http://www.w3.org/2000/01/rdf-schema#comment | "Pemphigus vulgaris (PV) is a severe autoimmune blistering skin disorder that is strongly associated with major histocompatibility complex class II alleles. Human leukocyte antigen (HLA) subtypes vary with racial/ethnic backgrounds. The purpose of this study was to determine the association of HLA class II alleles and haplotypes with PV in Turkish patients. Twenty-five patients with PV and 113 healthy transplant donors were genotyped for HLA class II alleles. HLA DNA typing was performed by the polymerase chain reaction/sequence specific primer method. The frequency of HLA DRB1*04 allele was 68.00% in patients compared to 30.97% in controls (P = 0.0012) and the frequency of HLA DRB1*14 allele was 32.00% in the patient group compared to 8.85% in the control group (P = 0.0054). Also, the frequency of HLA DRB1*04/DQB1*03 and HLA DRB1*14/DQB1*05 haplotypes in PV patients was significantly higher than controls (32.0% vs 6.2%, chi(2) = 28.142, P < 0.001; and 16% vs 2.7%, chi(2) = 15.143, P = 0.001, respectively). A preventive allele or haplotype for the manifestation of PV has not been identified in this study. Our findings suggest that HLA DRB1*04 and DRB1*14 alleles, and HLA DRB1*04/DQB1*03 and HLA DRB1*14/DQB1*05 haplotypes are genetic markers for general susceptibility to PV in the Turkish population."xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1346-8138.2009.00743.x"xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://purl.uniprot.org/core/author | "Tunca M."xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://purl.uniprot.org/core/author | "Akar A."xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://purl.uniprot.org/core/author | "Musabak U."xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://purl.uniprot.org/core/author | "Koc E."xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://purl.uniprot.org/core/author | "Sagkan R.I."xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20507388 | http://purl.uniprot.org/core/name | "J Dermatol"xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://purl.uniprot.org/core/pages | "246-250"xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://purl.uniprot.org/core/title | "Association of human leukocyte antigen class II alleles with pemphigus vulgaris in a Turkish population."xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://purl.uniprot.org/core/volume | "37"xsd:string |
| http://purl.uniprot.org/citations/20507388 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20507388 |
| http://purl.uniprot.org/citations/20507388 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20507388 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20507388 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20507388 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20507388 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC97-mappedCitation-20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20507388 |
| http://purl.uniprot.org/uniprot/#_A0A0E3DC99-mappedCitation-20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20507388 |
| http://purl.uniprot.org/uniprot/#_A0A076L4M5-mappedCitation-20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20507388 |
| http://purl.uniprot.org/uniprot/#_A0A0A0WDZ3-mappedCitation-20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20507388 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C7I5-mappedCitation-20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20507388 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C853-mappedCitation-20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20507388 |
| http://purl.uniprot.org/uniprot/#_A0A0A7CAC7-mappedCitation-20507388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20507388 |