| http://purl.uniprot.org/citations/20531392 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20531392 | http://www.w3.org/2000/01/rdf-schema#comment | "The protein Pex19p functions as a receptor and chaperone of peroxisomal membrane proteins (PMPs). The crystal structure of the folded C-terminal part of the receptor reveals a globular domain that displays a bundle of three long helices in an antiparallel arrangement. Complementary functional experiments, using a range of truncated Pex19p constructs, show that the structured alpha-helical domain binds PMP-targeting signal (mPTS) sequences with about 10 muM affinity. Removal of a conserved N-terminal helical segment from the mPTS recognition domain impairs the ability for mPTS binding, indicating that it forms part of the mPTS-binding site. Pex19p variants with mutations in the same sequence segment abolish correct cargo import. Our data indicate a divided N-terminal and C-terminal structural arrangement in Pex19p, which is reminiscent of a similar division in the Pex5p receptor, to allow separation of cargo-targeting signal recognition and additional functions."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.org/dc/terms/identifier | "doi:10.1038/emboj.2010.115"xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Wilmanns M."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Holton S.J."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Song Y.H."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Schliebs W."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Erdmann R."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Wolf J."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Stanley W.A."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Fodor K."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Milewski M."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Konarev P."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/author | "Schueller N."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/pages | "2491-2500"xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/title | "The peroxisomal receptor Pex19p forms a helical mPTS recognition domain."xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://purl.uniprot.org/core/volume | "29"xsd:string |
| http://purl.uniprot.org/citations/20531392 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20531392 |
| http://purl.uniprot.org/citations/20531392 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20531392 |
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| http://purl.uniprot.org/uniprot/#_P40855-mappedCitation-20531392 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20531392 |