http://purl.uniprot.org/citations/20557878 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20557878 | http://www.w3.org/2000/01/rdf-schema#comment | "The involvement of retinoblastoma protein-interacting zinc finger 1 (RIZ1), a tumor suppressor, in lipopolysaccharide (LPS)-induced inflammatory responses was investigated by using RAW 264.7 macrophage-like cells. LPS significantly augmented the expression of RIZ1 and the augmentation was mediated by the activation of nuclear factor (NF)-kappaB and Akt. The silencing of RIZ1 with the siRNA led to the inactivation of NF-kappaB in response to LPS. Moreover, the RIZ1 silencing caused the down-regulation of p53 activation and a p53 pharmacological inhibitor attenuated the RIZ1 expression. LPS-induced tumor necrosis factor-alpha and interleukin-6 production was prevented by RIZ1 siRNA or a p53 pharmacological inhibitor. Therefore, RIZ1 was suggested to augment LPS-induced NF-kappaB activation in collaboration with p53 and enhance the production of proinflammatory cytokines in response to LPS."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cellimm.2010.05.007"xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/author | "Komatsu T."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/author | "Yoshida T."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/author | "Naiki Y."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/author | "Yokochi T."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/author | "Koide N."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/author | "Tumurkhuu G."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/author | "Iftakhar-E-Khuda I."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/author | "Dagvadorj J."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/author | "Noman A.S."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/name | "Cell Immunol"xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/pages | "114-118"xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/title | "Retinoblastoma protein-interacting zinc finger 1, a tumor suppressor, augments lipopolysaccharide-induced proinflammatory cytokine production via enhancing nuclear factor-kappaB activation."xsd:string |
http://purl.uniprot.org/citations/20557878 | http://purl.uniprot.org/core/volume | "264"xsd:string |
http://purl.uniprot.org/citations/20557878 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20557878 |
http://purl.uniprot.org/citations/20557878 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20557878 |
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http://purl.uniprot.org/uniprot/#_Q80VF3-mappedCitation-20557878 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20557878 |