http://purl.uniprot.org/citations/20562265 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20562265 | http://www.w3.org/2000/01/rdf-schema#comment | "Accumulating evidence suggests that CD4 help is needed at the memory stage to mount effective secondary CD8 T cell responses. In this paper, we report that memory CD4 T cells can provide efficient help to memory CD8 T cells after interaction of the two lymphocytes with distinct dendritic cells. Provision of help to CD8 T cells required direct cell-cell contact and involved both IL-2 and CD40 ligation, within a CD4-CD8 T cell synapse. Thus, following antigenic interaction with APCs, activated memory CD4 and CD8 T cells appear to separate from their respective APCs before meeting each other for help provision, regardless of their Ag specificity. CD4 help for memory CD8 T cells therefore appears to be conditioned primarily not by Ag specificity but by activation status."xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.0904209"xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/author | "Vallee M."xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/author | "Cariou A."xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/author | "Taoufik Y."xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/author | "de Goer de Herve M.G."xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/author | "Herr F."xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/author | "Dembele B."xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/pages | "1028-1036"xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/title | "Direct CD4 help provision following interaction of memory CD4 and CD8 T cells with distinct antigen-presenting dendritic cells."xsd:string |
http://purl.uniprot.org/citations/20562265 | http://purl.uniprot.org/core/volume | "185"xsd:string |
http://purl.uniprot.org/citations/20562265 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20562265 |
http://purl.uniprot.org/citations/20562265 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20562265 |
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