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http://purl.uniprot.org/citations/20589901 | http://www.w3.org/2000/01/rdf-schema#comment | "During limb development, the dorsal limb mesenchyme expression of the transcription factor LMX1B is required for dorsoventral limb patterning. In mice, Lmx1b mutations result in the mirror-image duplication of ventral limb structures and loss of dorsal limb structures. Heterozygous LMX1B mutations in humans cause the Nail-Patella Syndrome characterized by limb, kidney, and eye developmental defects. We used DNA microarrays to compare the mRNAs in E13.5 mouse Lmx1b mutant and wild-type limbs. We report 14 genes that require Lmx1b for their normal expression in the dorsal limb or the restriction of their expression to the ventral limb."xsd:string |
http://purl.uniprot.org/citations/20589901 | http://purl.org/dc/terms/identifier | "doi:10.1002/dvdy.22357"xsd:string |
http://purl.uniprot.org/citations/20589901 | http://purl.uniprot.org/core/author | "Kania A."xsd:string |
http://purl.uniprot.org/citations/20589901 | http://purl.uniprot.org/core/author | "Gu W.X."xsd:string |
http://purl.uniprot.org/citations/20589901 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20589901 | http://purl.uniprot.org/core/name | "Dev Dyn"xsd:string |
http://purl.uniprot.org/citations/20589901 | http://purl.uniprot.org/core/pages | "2246-2255"xsd:string |
http://purl.uniprot.org/citations/20589901 | http://purl.uniprot.org/core/title | "Identification of genes controlled by LMX1B in E13.5 mouse limbs."xsd:string |
http://purl.uniprot.org/citations/20589901 | http://purl.uniprot.org/core/volume | "239"xsd:string |
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