| http://purl.uniprot.org/citations/20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20591429 | http://www.w3.org/2000/01/rdf-schema#comment | "S100 proteins interact with the transactivation domain and the C-terminus of p53. Further, S100B has been shown to interact with MDM2, a central negative regulator of p53. Here, we show that S100B bound directly to the folded N-terminal domain of MDM2 (residues 2-125) by size exclusion chromatography and surface plasmon resonance experiments. This interaction with MDM2 (2-125) is a general feature of S100 proteins; S100A1, S100A2, S100A4 and S100A6 also interact with MDM2 (2-125). These interactions with S100 proteins do not result in a ternary complex with MDM2 (2-125) and p53. Instead, we observe the ability of a subset of S100 proteins to disrupt the extent of MDM2-mediated p53 ubiquitylation in vitro."xsd:string |
| http://purl.uniprot.org/citations/20591429 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2010.06.024"xsd:string |
| http://purl.uniprot.org/citations/20591429 | http://purl.uniprot.org/core/author | "Fersht A.R."xsd:string |
| http://purl.uniprot.org/citations/20591429 | http://purl.uniprot.org/core/author | "Teufel D.P."xsd:string |
| http://purl.uniprot.org/citations/20591429 | http://purl.uniprot.org/core/author | "van Dieck J."xsd:string |
| http://purl.uniprot.org/citations/20591429 | http://purl.uniprot.org/core/author | "Lum J.K."xsd:string |
| http://purl.uniprot.org/citations/20591429 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20591429 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/20591429 | http://purl.uniprot.org/core/pages | "3269-3274"xsd:string |
| http://purl.uniprot.org/citations/20591429 | http://purl.uniprot.org/core/title | "S100 proteins interact with the N-terminal domain of MDM2."xsd:string |
| http://purl.uniprot.org/citations/20591429 | http://purl.uniprot.org/core/volume | "584"xsd:string |
| http://purl.uniprot.org/citations/20591429 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20591429 |
| http://purl.uniprot.org/citations/20591429 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20591429 |
| http://purl.uniprot.org/uniprot/#_A0A0S2Z4C5-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |
| http://purl.uniprot.org/uniprot/#_A0A0S2Z4H2-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |
| http://purl.uniprot.org/uniprot/#_A8MRB1-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |
| http://purl.uniprot.org/uniprot/#_B2R577-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |
| http://purl.uniprot.org/uniprot/#_P04271-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |
| http://purl.uniprot.org/uniprot/#_Q5Q9Z3-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |
| http://purl.uniprot.org/uniprot/#_P23297-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |
| http://purl.uniprot.org/uniprot/#_P29034-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |
| http://purl.uniprot.org/uniprot/#_P06703-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |
| http://purl.uniprot.org/uniprot/#_P04637-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |
| http://purl.uniprot.org/uniprot/#_P26447-mappedCitation-20591429 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20591429 |