http://purl.uniprot.org/citations/20591987 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20591987 | http://www.w3.org/2000/01/rdf-schema#comment | "BackgroundAssociation of the HLA-DRB1*1501 allele with multiple sclerosis is well established, but its association with neuromyelitis optica has only been evaluated in small populations.MethodsWe performed a case-control genetic association study to evaluate the association of HLA-DRB1*1501 with neuromyelitis optica. The single nucleotide polymorphism rs3135388, which tags HLA-DRB1*1501, was genotyped in 164 patients with neuromyelitis optica, 220 patients with multiple sclerosis and 959 controls matched for age, gender and ethnicity. Genotyping for rs3135388 was performed by Taqman-based 5' nuclease assay.ResultsRs3135388*A was positively associated with multiple sclerosis (OR = 3.93; 95% CI = 2.58-5.97, p = 1.18 x 10(-09)) but negatively associated with NMO (OR = 0.57; 95% CI = 0.36-0.91, p = 0.01).ConclusionsMultiple sclerosis and neuromyelitis optica differ in their associations with DRB1*1501."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.org/dc/terms/identifier | "doi:10.1177/1352458510374340"xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Cross A."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Parry G."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Jacob A."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Piccio L."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Atkinson E.J."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Lang W."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Boggild M."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Kristoferitsch W."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Kingsbury D.J."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Scott T."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Schaefer-Klein J."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Weinshenker B.G."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Kantarci O.H."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Barreira A.A."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Brum D.G."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Pardo G."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Paul F."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Matiello M."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/author | "Jarius S."xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/name | "Mult Scler"xsd:string |
http://purl.uniprot.org/citations/20591987 | http://purl.uniprot.org/core/pages | "981-984"xsd:string |