| http://purl.uniprot.org/citations/20601428 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20601428 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20601428 | http://www.w3.org/2000/01/rdf-schema#comment | "In humans the mitochondrial inner membrane protein Oxa1L is involved in the biogenesis of membrane proteins and facilitates the insertion of both mitochondrial- and nuclear-encoded proteins from the mitochondrial matrix into the inner membrane. The C-terminal approximately 100-amino acid tail of Oxa1L (Oxa1L-CTT) binds to mitochondrial ribosomes and plays a role in the co-translational insertion of mitochondria-synthesized proteins into the inner membrane. Contrary to suggestions made for yeast Oxa1p, our results indicate that the C-terminal tail of human Oxa1L does not form a coiled-coil helical structure in solution. The Oxa1L-CTT exists primarily as a monomer in solution but forms dimers and tetramers at high salt concentrations. The binding of Oxa1L-CTT to mitochondrial ribosomes is an enthalpy-driven process with a K(d) of 0.3-0.8 microM and a stoichiometry of 2. Oxa1L-CTT cross-links to mammalian mitochondrial homologs of the bacterial ribosomal proteins L13, L20, and L28 and to mammalian mitochondrial specific ribosomal proteins MRPL48, MRPL49, and MRPL51. Oxa1L-CTT does not cross-link to proteins decorating the conventional exit tunnel of the bacterial large ribosomal subunit (L22, L23, L24, and L29)."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m110.148262"xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m110.148262"xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Spremulli L.L."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Spremulli L.L."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Haque M.E."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Haque M.E."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Koc E.C."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Koc E.C."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Koc H."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Koc H."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Tripathy A."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Tripathy A."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Elmore K.B."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/author | "Elmore K.B."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/pages | "28353-28362"xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/pages | "28353-28362"xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/title | "Properties of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L and its interactions with mammalian mitochondrial ribosomes."xsd:string |
| http://purl.uniprot.org/citations/20601428 | http://purl.uniprot.org/core/title | "Properties of the C-terminal tail of human mitochondrial inner membrane protein Oxa1L and its interactions with mammalian mitochondrial ribosomes."xsd:string |