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| http://purl.uniprot.org/citations/20621096 | http://www.w3.org/2000/01/rdf-schema#comment | "The 5' cap trimethylation of small nuclear (snRNAs) and several nucleolar RNAs (snoRNAs) by trimethylguanosine synthase 1 (Tgs1p) is required for efficient pre-mRNA splicing. The previously uncharacterised protein Swm2p interacted with Tgs1p in yeast two-hybrid screens. In the present study we show that Swm2p interacts with the N-terminus of Tgs1p and its deletion impairs pre-mRNA splicing and pre-rRNA processing. The trimethylation of spliceosomal snRNAs and the U3 snoRNA, but not other snoRNAs, was abolished in the absence of Swm2p, indicating that Swm2p is required for a substrate-specific activity of Tgs1p."xsd:string |
| http://purl.uniprot.org/citations/20621096 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2010.07.001"xsd:string |
| http://purl.uniprot.org/citations/20621096 | http://purl.uniprot.org/core/author | "Kos M."xsd:string |
| http://purl.uniprot.org/citations/20621096 | http://purl.uniprot.org/core/author | "Boon K.L."xsd:string |
| http://purl.uniprot.org/citations/20621096 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20621096 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/20621096 | http://purl.uniprot.org/core/pages | "3299-3304"xsd:string |
| http://purl.uniprot.org/citations/20621096 | http://purl.uniprot.org/core/title | "Deletion of Swm2p selectively impairs trimethylation of snRNAs by trimethylguanosine synthase (Tgs1p)."xsd:string |
| http://purl.uniprot.org/citations/20621096 | http://purl.uniprot.org/core/volume | "584"xsd:string |
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