| http://purl.uniprot.org/citations/20622878 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20622878 | http://www.w3.org/2000/01/rdf-schema#comment | "Behçet's disease is a genetically complex disease of unknown etiology characterized by recurrent inflammatory attacks affecting the orogenital mucosa, eyes and skin. We performed a genome-wide association study with 311,459 SNPs in 1,215 individuals with Behçet's disease (cases) and 1,278 healthy controls from Turkey. We confirmed the known association of Behçet's disease with HLA-B*51 and identified a second, independent association within the MHC Class I region. We also identified an association at IL10 (rs1518111, P = 1.88 x 10(-8)). Using a meta-analysis with an additional five cohorts from Turkey, the Middle East, Europe and Asia, comprising a total of 2,430 cases and 2,660 controls, we identified associations at IL10 (rs1518111, P = 3.54 x 10(-18), odds ratio = 1.45, 95% CI 1.34-1.58) and the IL23R-IL12RB2 locus (rs924080, P = 6.69 x 10(-9), OR = 1.28, 95% CI 1.18-1.39). The disease-associated IL10 variant (the rs1518111 A allele) was associated with diminished mRNA expression and low protein production."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng.625"xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Chen W."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Yang B."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Kirino Y."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Amos C.I."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Gadina M."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Kastner D.L."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Remmers E.F."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Cho Y.H."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Gul A."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Dizon M.B."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Cakiris A."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Ustek D."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Abaci N."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Emrence Z."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Erer B."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Ombrello M.J."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Satorius C."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Tugal-Tutkun I."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Korman B.D."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Ben-Chetrit E."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Le J.M."xsd:string |
| http://purl.uniprot.org/citations/20622878 | http://purl.uniprot.org/core/author | "Kaklamani V.G."xsd:string |