| http://purl.uniprot.org/citations/20628061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20628061 | http://www.w3.org/2000/01/rdf-schema#comment | "Aquaporins facilitate efficient diffusion of water across cellular membranes, and water homeostasis is critically important in conditions such as cerebral edema. Changes in aquaporin 1 and 4 expression in the brain are associated with cerebral edema, and the lack of water channel modulators is often highlighted. Here we present evidence of an endogenous modulator of aquaporin 1 and 4. We identify miR-320a as a potential modulator of aquaporin 1 and 4 and explore the possibility of using miR-320a to alter the expression of aquaporin 1 and 4 in normal and ischemic conditions. We show that precursor miR-320a can function as an inhibitor, whereas anti-miR-320a can act as an activator of aquaporin 1 and 4 expressions. We have also shown that anti-miR-320a could bring about a reduction of infarct volume in cerebral ischemia with a concomitant increase in aquaporins 1 and 4 mRNA and protein expression."xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m110.144576"xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/author | "Armugam A."xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/author | "Jeyaseelan K."xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/author | "Lim K.Y."xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/author | "Tan J.R."xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/author | "Karolina D.S."xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/author | "Sepramaniam S."xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/author | "Swaminathan P."xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/pages | "29223-29230"xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/title | "MicroRNA 320a functions as a novel endogenous modulator of aquaporins 1 and 4 as well as a potential therapeutic target in cerebral ischemia."xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://purl.uniprot.org/core/volume | "285"xsd:string |
| http://purl.uniprot.org/citations/20628061 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20628061 |
| http://purl.uniprot.org/citations/20628061 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20628061 |
| http://purl.uniprot.org/uniprot/#_A0A5F9ZHR4-mappedCitation-20628061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20628061 |
| http://purl.uniprot.org/uniprot/#_B4DHF5-mappedCitation-20628061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20628061 |
| http://purl.uniprot.org/uniprot/#_F1DSG4-mappedCitation-20628061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20628061 |
| http://purl.uniprot.org/uniprot/#_Q53H97-mappedCitation-20628061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20628061 |
| http://purl.uniprot.org/uniprot/#_P55087-mappedCitation-20628061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20628061 |
| http://purl.uniprot.org/uniprot/#_Q59GF3-mappedCitation-20628061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20628061 |
| http://purl.uniprot.org/uniprot/#_Q6L7A0-mappedCitation-20628061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20628061 |
| http://purl.uniprot.org/uniprot/#_Q9H3V7-mappedCitation-20628061 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20628061 |