http://purl.uniprot.org/citations/20631175 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20631175 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20631175 | http://www.w3.org/2000/01/rdf-schema#comment | "Neonatal breathing in mammals involves multiple neuronal circuits, but its genetic basis remains unclear. Mice deficient for the zinc finger protein Teashirt 3 (TSHZ3) fail to breathe and die at birth. Tshz3 is expressed in multiple areas of the brainstem involved in respiration, including the pre-Bötzinger complex (preBötC), the embryonic parafacial respiratory group (e-pF), and cranial motoneurons that control the upper airways. Tshz3 inactivation led to pronounced cell death of motoneurons in the nucleus ambiguus and induced strong alterations of rhythmogenesis in the e-pF oscillator. In contrast, the preBötC oscillator appeared to be unaffected. These deficits result in impaired upper airway function, abnormal central respiratory rhythm generation, and altered responses to pH changes. Thus, a single gene, Tshz3, controls the development of diverse components of the circuitry required for breathing."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.org/dc/terms/identifier | "doi:10.1523/jneurosci.1765-10.2010"xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.org/dc/terms/identifier | "doi:10.1523/jneurosci.1765-10.2010"xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Faralli H."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Faralli H."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Caubit X."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Caubit X."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Fasano L."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Fasano L."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Thoby-Brisson M."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Thoby-Brisson M."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Fortin G."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Fortin G."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Bevengut M."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Bevengut M."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Hilaire G."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Hilaire G."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Filippi P."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Filippi P."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Voituron N."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Voituron N."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Zanella S."xsd:string |
http://purl.uniprot.org/citations/20631175 | http://purl.uniprot.org/core/author | "Zanella S."xsd:string |