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http://purl.uniprot.org/citations/20659015 | http://www.w3.org/2000/01/rdf-schema#comment | "How RNA-binding proteins recognize their complement of targets in a complex cellular environment remains poorly understood. Sequence degeneracy and redundancy of short motifs at genomic scales have mostly eluded predictions of specific target genes for gene-specific ELAV (embryonic lethal abnormal visual system)/Hu proteins that bind ubiquitous AU-rich motifs. Using the genetic tools of Drosophila, we have analysed binding properties of ELAV in vitro and ELAV-dependent regulation of its major target ewg (erect wing) in neurons. These studies reveal that an integral part of ELAV gene-specific regulation involves combinatorial binding to variably spaced short U-rich motifs on an extensive binding site."xsd:string |
http://purl.uniprot.org/citations/20659015 | http://purl.org/dc/terms/identifier | "doi:10.1042/bst0381122"xsd:string |
http://purl.uniprot.org/citations/20659015 | http://purl.uniprot.org/core/author | "Li M."xsd:string |
http://purl.uniprot.org/citations/20659015 | http://purl.uniprot.org/core/author | "Haussmann I.U."xsd:string |
http://purl.uniprot.org/citations/20659015 | http://purl.uniprot.org/core/author | "Soller M."xsd:string |
http://purl.uniprot.org/citations/20659015 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20659015 | http://purl.uniprot.org/core/name | "Biochem Soc Trans"xsd:string |
http://purl.uniprot.org/citations/20659015 | http://purl.uniprot.org/core/pages | "1122-1124"xsd:string |
http://purl.uniprot.org/citations/20659015 | http://purl.uniprot.org/core/title | "Determinants of ELAV gene-specific regulation."xsd:string |
http://purl.uniprot.org/citations/20659015 | http://purl.uniprot.org/core/volume | "38"xsd:string |
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