| http://purl.uniprot.org/citations/20671156 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20671156 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20671156 | http://www.w3.org/2000/01/rdf-schema#comment | "Fanconi anemia (FA) is caused by mutations in 13 Fanc genes and renders cells hypersensitive to DNA interstrand cross-linking (ICL) agents. A central event in the FA pathway is mono-ubiquitylation of the FANCI-FANCD2 (ID) protein complex. Here, we characterize a previously unrecognized nuclease, Fanconi anemia-associated nuclease 1 (FAN1), that promotes ICL repair in a manner strictly dependent on its ability to accumulate at or near sites of DNA damage and that relies on mono-ubiquitylation of the ID complex. Thus, the mono-ubiquitylated ID complex recruits the downstream repair protein FAN1 and facilitates the repair of DNA interstrand cross-links."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1192656"xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1192656"xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/author | "Chen J."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/author | "Chen J."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/author | "Huang J."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/author | "Huang J."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/author | "Liu T."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/author | "Liu T."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/author | "Yuan J."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/author | "Yuan J."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/author | "Ghosal G."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/author | "Ghosal G."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/pages | "693-696"xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/pages | "693-696"xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/title | "FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/title | "FAN1 acts with FANCI-FANCD2 to promote DNA interstrand cross-link repair."xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/volume | "329"xsd:string |
| http://purl.uniprot.org/citations/20671156 | http://purl.uniprot.org/core/volume | "329"xsd:string |