| http://purl.uniprot.org/citations/20675586 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20675586 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20675586 | http://www.w3.org/2000/01/rdf-schema#comment | "To the mounting evidence of nonribosomal functions for ribosomal proteins, we now add L7Ae as a subunit of archaeal RNase P, a ribonucleoprotein (RNP) that catalyzes 5'-maturation of precursor tRNAs (pre-tRNAs). We first demonstrate that L7Ae coelutes with partially purified Methanococcus maripaludis (Mma) RNase P activity. After establishing in vitro reconstitution of the single RNA with four previously known protein subunits (POP5, RPP21, RPP29, and RPP30), we show that addition of L7Ae to this RNase P complex increases the optimal reaction temperature and k(cat)/K(m) (by approximately 360-fold) for pre-tRNA cleavage to those observed with partially purified native Mma RNase P. We identify in the Mma RNase P RNA a putative kink-turn (K-turn), the structural motif recognized by L7Ae. The large stimulatory effect of Mma L7Ae on RNase P activity decreases to xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.1005556107"xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.1005556107"xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/author | "Mukhopadhyay B."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/author | "Mukhopadhyay B."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/author | "Susanti D."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/author | "Susanti D."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/author | "Gopalan V."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/author | "Gopalan V."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/author | "Cho I.M."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/author | "Cho I.M."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/author | "Lai L.B."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/author | "Lai L.B."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/pages | "14573-14578"xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/pages | "14573-14578"xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/title | "Ribosomal protein L7Ae is a subunit of archaeal RNase P."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/title | "Ribosomal protein L7Ae is a subunit of archaeal RNase P."xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/volume | "107"xsd:string |
| http://purl.uniprot.org/citations/20675586 | http://purl.uniprot.org/core/volume | "107"xsd:string |