| http://purl.uniprot.org/citations/20680483 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20680483 | http://www.w3.org/2000/01/rdf-schema#comment | "Neurotrophin receptors utilize specific adaptor proteins to activate signaling pathways involved in various neuronal functions, such as neurite outgrowth and cytoskeletal remodeling. The Ankyrin-Repeat Rich Membrane Spanning (ARMS)/kinase D-interacting substrate-220 kDa (Kidins220) serves as a unique downstream adaptor protein of Trk receptor tyrosine kinases. To gain insight into the role of ARMS/Kidins220, a yeast two-hybrid screen of a rat dorsal root ganglion library was performed using the C-terminal region of ARMS/Kidins220 as bait. The screen identified a mammalian septin, Septin 5 (Sept5), as an interacting protein. Co-immunoprecipitation using lysates from transiently transfected HEK-293 cells revealed the specific interaction between ARMS/Kidins220 and Sept5. Endogenous ARMS/Kidins220 and Sept5 proteins were colocalized in primary hippocampal neurons and were also predominantly expressed at the plasma membrane and in the tips of growing neurites in nerve growth factor-treated PC12 cells. Mapping of Sept5 domains important for ARMS/Kidins220 binding revealed a highly conserved N-terminal region of Sept5. The direct interaction between ARMS/Kidins220 and Sept5 suggests a possible role of ARMS/Kidins220 as a functional link between neurotrophin receptors and septins to mediate neurotrophin-induced intracellular signaling events, such as neurite outgrowth and cytoskeletal remodeling."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10059-010-0099-7"xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/author | "Lee S.J."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/author | "Park Y.S."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/author | "Lee S.P."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/author | "Park H.W."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/author | "Chang M.S."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/author | "Chao M.V."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/author | "Park H.J."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/author | "Arevalo J.C."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/author | "Paik K.S."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/name | "Mol Cells"xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/pages | "143-148"xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/title | "Ankyrin repeat-rich membrane spanning/Kidins220 protein interacts with mammalian Septin 5."xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://purl.uniprot.org/core/volume | "30"xsd:string |
| http://purl.uniprot.org/citations/20680483 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20680483 |
| http://purl.uniprot.org/citations/20680483 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20680483 |
| http://purl.uniprot.org/uniprot/#_D3ZDH8-mappedCitation-20680483 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20680483 |
| http://purl.uniprot.org/uniprot/#_A6JSF1-mappedCitation-20680483 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20680483 |
| http://purl.uniprot.org/uniprot/#_A6JSF2-mappedCitation-20680483 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20680483 |
| http://purl.uniprot.org/uniprot/#_A6JSF3-mappedCitation-20680483 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20680483 |
| http://purl.uniprot.org/uniprot/#_A6JSF4-mappedCitation-20680483 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20680483 |
| http://purl.uniprot.org/uniprot/#_A6JSF5-mappedCitation-20680483 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20680483 |