| http://purl.uniprot.org/citations/20706207 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20706207 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20706207 | http://www.w3.org/2000/01/rdf-schema#comment | "Cell proliferation is the main driving force for plant growth. Although genome sequence analysis revealed a high number of cell cycle genes in plants, little is known about the molecular complexes steering cell division. In a targeted proteomics approach, we mapped the core complex machinery at the heart of the Arabidopsis thaliana cell cycle control. Besides a central regulatory network of core complexes, we distinguished a peripheral network that links the core machinery to up- and downstream pathways. Over 100 new candidate cell cycle proteins were predicted and an in-depth biological interpretation demonstrated the hypothesis-generating power of the interaction data. The data set provided a comprehensive view on heterodimeric cyclin-dependent kinase (CDK)-cyclin complexes in plants. For the first time, inhibitory proteins of plant-specific B-type CDKs were discovered and the anaphase-promoting complex was characterized and extended. Important conclusions were that mitotic A- and B-type cyclins form complexes with the plant-specific B-type CDKs and not with CDKA;1, and that D-type cyclins and S-phase-specific A-type cyclins seem to be associated exclusively with CDKA;1. Furthermore, we could show that plants have evolved a combinatorial toolkit consisting of at least 92 different CDK-cyclin complex variants, which strongly underscores the functional diversification among the large family of cyclins and reflects the pivotal role of cell cycle regulation in the developmental plasticity of plants."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.org/dc/terms/identifier | "doi:10.1038/msb.2010.53"xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.org/dc/terms/identifier | "doi:10.1038/msb.2010.53"xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "De Jaeger G."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "De Jaeger G."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Hilson P."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Hilson P."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Inze D."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Inze D."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Meyer C."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Meyer C."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Van Isterdael G."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Van Isterdael G."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Van de Peer Y."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Van de Peer Y."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Beynon J."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Beynon J."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Faure J.-D."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Faure J.-D."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Renne C."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Renne C."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Van Onckelen H."xsd:string |
| http://purl.uniprot.org/citations/20706207 | http://purl.uniprot.org/core/author | "Van Onckelen H."xsd:string |