| http://purl.uniprot.org/citations/20726779 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20726779 | http://www.w3.org/2000/01/rdf-schema#comment | "The budding yeast Saccharomyces cerevisiae grows far better at acidic than at neutral or alkaline pH. Consequently, even a modest alkalinization of the medium represents a stressful situation for this yeast. In the past few years, data generated by a combination of genome-wide techniques has demonstrated that adaptive responses of S. cerevisiae to high pH stress involves extensive gene remodeling as a result of the fast activation of a number of stress-related signaling pathways, such as the Rim101, the Wsc1-Pkc1-Slt2 MAP kinase, and the calcium-activated calcineurin pathways. Alkalinization of the environment also disturbs nutrient homeostasis, as deduced from its impact on iron/copper, phosphate, and glucose uptake/utilization pathways. In this review we will examine these responses, their possible interactions, and the role that they play in tolerance to high pH stress."xsd:string |
| http://purl.uniprot.org/citations/20726779 | http://purl.org/dc/terms/identifier | "doi:10.1089/omi.2010.0044"xsd:string |
| http://purl.uniprot.org/citations/20726779 | http://purl.uniprot.org/core/author | "Arino J."xsd:string |
| http://purl.uniprot.org/citations/20726779 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20726779 | http://purl.uniprot.org/core/name | "OMICS"xsd:string |
| http://purl.uniprot.org/citations/20726779 | http://purl.uniprot.org/core/pages | "517-523"xsd:string |
| http://purl.uniprot.org/citations/20726779 | http://purl.uniprot.org/core/title | "Integrative responses to high pH stress in S. cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/20726779 | http://purl.uniprot.org/core/volume | "14"xsd:string |
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