RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/20729859http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20729859http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20729859http://www.w3.org/2000/01/rdf-schema#comment"BRCA2 is a tumor suppressor that functions in homologous recombination, a key genomic integrity pathway. BRCA2 interacts with RAD51, the central protein of recombination, which forms filaments on single-stranded DNA (ssDNA) to perform homology search and DNA strand invasion. We report the purification of full-length human BRCA2 and show that it binds to ~6 RAD51 molecules and promotes RAD51 binding to ssDNA coated by replication protein A (RPA), in a manner that is stimulated by DSS1."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.org/dc/terms/identifier"doi:10.1038/nsmb.1904"xsd:string
http://purl.uniprot.org/citations/20729859http://purl.org/dc/terms/identifier"doi:10.1038/nsmb.1904"xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/author"Liu J."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/author"Liu J."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/author"Gibson B."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/author"Gibson B."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/author"Heyer W.D."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/author"Heyer W.D."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/author"Doty T."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/author"Doty T."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/name"Nat. Struct. Mol. Biol."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/name"Nat. Struct. Mol. Biol."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/pages"1260-1262"xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/pages"1260-1262"xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/title"Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/title"Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA."xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/volume"17"xsd:string
http://purl.uniprot.org/citations/20729859http://purl.uniprot.org/core/volume"17"xsd:string
http://purl.uniprot.org/citations/20729859http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20729859
http://purl.uniprot.org/citations/20729859http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20729859