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http://purl.uniprot.org/citations/20812917http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20812917http://www.w3.org/2000/01/rdf-schema#comment"CS (chondroitin sulfate) is a glycosaminoglycan species that is widely distributed in the extracellular matrix. To understand the physiological roles of enzymes involved in CS synthesis, we produced CSGalNAcT1 (CS N-acetylgalactosaminyltransferase 1)-null mice. CS production was reduced by approximately half in CSGalNAcT1-null mice, and the amount of short-chain CS was also reduced. Moreover, the cartilage of the null mice was significantly smaller than that of wild-type mice. Additionally, type-II collagen fibres in developing cartilage were abnormally aggregated and disarranged in the homozygous mutant mice. These results suggest that CSGalNAcT1 is required for normal CS production in developing cartilage."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.org/dc/terms/identifier"doi:10.1042/bj20100847"xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Hasegawa A."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Kitagawa H."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Li M."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Sato M."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Watanabe Y."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Takeuchi K."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Yokoyama M."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Abe M."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Furuichi T."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Igarashi M."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Tsujita M."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Natsume R."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Sakimura K."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Ikegawa S."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Saeki M."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Izumikawa T."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Amizuka N."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/author"Higa Onaga S."xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/name"Biochem J"xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/pages"47-55"xsd:string
http://purl.uniprot.org/citations/20812917http://purl.uniprot.org/core/title"Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development."xsd:string