| http://purl.uniprot.org/citations/20818381 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20818381 | http://www.w3.org/2000/01/rdf-schema#comment | "We conducted a genome-wide association study of type 2 diabetes (T2D) using 459,359 SNPs in a Japanese population with a three-stage study design (stage 1, 4,470 cases and 3,071 controls; stage 2, 2,886 cases and 3,087 controls; stage 3, 3,622 cases and 2,356 controls). We identified new associations in UBE2E2 on chromosome 3 and in C2CD4A-C2CD4B on chromosome 15 at genome-wide significant levels (rs7612463 in UBE2E2, combined P = 2.27 × 10⁻⁹; rs7172432 in C2CD4A-C2CD4B, combined P = 3.66 × 10⁻⁹). The association of these two loci with T2D was replicated in other east Asian populations. In the European populations, the C2CD4A-C2CD4B locus was significantly associated with T2D, and a combined analysis of all populations gave P = 8.78 × 10⁻¹⁴, whereas the UBE2E2 locus did not show association to T2D. In conclusion, we identified two new loci at UBE2E2 and C2CD4A-C2CD4B associated with susceptibility to T2D."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng.660"xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Hansen T."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Kashiwagi A."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Kasuga M."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Hara K."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Kubo M."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Nakamura Y."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Fujita H."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Maeda S."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Nakamura M."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Tanaka Y."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Yasuda K."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Park K.S."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Jorgensen T."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Hirose H."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Kadowaki T."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Saito I."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Takahashi A."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Iwabu M."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Okada-Iwabu M."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Yamauchi T."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Froguel P."xsd:string |
| http://purl.uniprot.org/citations/20818381 | http://purl.uniprot.org/core/author | "Pedersen O."xsd:string |