| http://purl.uniprot.org/citations/20826443 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20826443 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20826443 | http://www.w3.org/2000/01/rdf-schema#comment | "The leucine-rich repeat (LRR) proteins LRIM1 and APL1C control the function of the complement-like protein TEP1 in Anopheles mosquitoes. The molecular structure of LRIM1 and APL1C and the basis of their interaction with TEP1 represent a new type of innate immune complex. The LRIM1/APL1C complex specifically binds and solubilizes a cleaved form of TEP1 without an intact thioester bond. The LRIM1 and APL1C LRR domains have a large radius of curvature, glycosylated concave face, and a novel C-terminal capping motif. The LRIM1/APL1C complex is a heterodimer with a single intermolecular disulfide bond. The structure of the LRIM1/APL1C heterodimer reveals an interface between the two LRR domains and an extensive C-terminal coiled-coil domain. We propose that a cleaved form of TEP1 may act as a convertase for activation of other TEP1 molecules and that the LRIM1/APL1C heterodimer regulates formation of this TEP1 convertase."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.1010575107"xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.1010575107"xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Levashina E.A."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Levashina E.A."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Deisenhofer J."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Deisenhofer J."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Chelliah Y."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Chelliah Y."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Volohonsky G."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Volohonsky G."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Baxter R.H."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Baxter R.H."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Steinert S."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/author | "Steinert S."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/pages | "16817-16822"xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/pages | "16817-16822"xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/title | "A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae."xsd:string |
| http://purl.uniprot.org/citations/20826443 | http://purl.uniprot.org/core/title | "A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae."xsd:string |