| http://purl.uniprot.org/citations/20828131 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20828131 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20828131 | http://www.w3.org/2000/01/rdf-schema#comment | "We present a strategy to solve the high-resolution structure of amyloid fibrils by solid-state NMR and use it to determine the atomic-resolution structure of the prion domain of the fungal prion HET-s in its amyloid form. On the basis of 134 unambiguous distance restraints, we recently showed that HET-s(218-289) in its fibrillar state forms a left-handed β-solenoid, and an atomic-resolution NMR structure of the triangular core was determined from unambiguous restraints only. In this paper, we go considerably further and present a comprehensive protocol using six differently labeled samples, a collection of optimized solid-state NMR experiments, and adapted structure calculation protocols. The high-resolution structure obtained includes the less ordered but biologically important C-terminal part and improves the overall accuracy by including a large number of ambiguous distance restraints."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.org/dc/terms/identifier | "doi:10.1021/ja104213j"xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.org/dc/terms/identifier | "doi:10.1021/ja104213j"xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Loquet A."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Loquet A."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Ab E."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Ab E."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Van Melckebeke H."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Van Melckebeke H."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Bockmann A."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Bockmann A."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Lange A."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Lange A."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Meier B.H."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Meier B.H."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Wasmer C."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/author | "Wasmer C."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/name | "J. Am. Chem. Soc."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/name | "J. Am. Chem. Soc."xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/pages | "13765-13775"xsd:string |
| http://purl.uniprot.org/citations/20828131 | http://purl.uniprot.org/core/pages | "13765-13775"xsd:string |