| http://purl.uniprot.org/citations/20843791 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20843791 | http://www.w3.org/2000/01/rdf-schema#comment | "Plasma membrane compartmentalization spatiotemporally regulates cell-autonomous immune signaling in animal cells. To elucidate immediate early protein dynamics at the plant plasma membrane in response to the bacterial pathogen-associated molecular pattern (PAMP) flagellin (flg22) we employed quantitative mass spectrometric analysis on detergent-resistant membranes (DRMs) of Arabidopsis thaliana suspension cells. This approach revealed rapid and profound changes in DRM protein composition following PAMP treatment, prominently affecting proton ATPases and receptor-like kinases, including the flagellin receptor FLS2. We employed reverse genetics to address a potential contribution of a subset of these proteins in flg22-triggered cellular responses. Mutants of three candidates (DET3, AHA1, FER) exhibited a conspicuous defect in the PAMP-triggered accumulation of reactive oxygen species. In addition, these mutants showed altered mitogen-activated protein kinase (MAPK) activation, a defect in PAMP-triggered stomatal closure as well as altered bacterial infection phenotypes, which revealed three novel players in elicitor-dependent oxidative burst control and innate immunity. Our data provide evidence for dynamic elicitor-induced changes in the membrane compartmentalization of PAMP signaling components."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m110.160531"xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/author | "Grossniklaus U."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/author | "Panstruga R."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/author | "Schulze W.X."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/author | "Robatzek S."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/author | "Kessler S.A."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/author | "Shimosato-Asano H."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/author | "Keinath N.F."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/author | "Bourdais G."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/author | "Lorek J."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/author | "Kierszniowska S."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/pages | "39140-39149"xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/title | "PAMP (pathogen-associated molecular pattern)-induced changes in plasma membrane compartmentalization reveal novel components of plant immunity."xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://purl.uniprot.org/core/volume | "285"xsd:string |
| http://purl.uniprot.org/citations/20843791 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20843791 |
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| http://purl.uniprot.org/uniprot/#_Q9FL28-mappedCitation-20843791 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20843791 |
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