http://purl.uniprot.org/citations/20850383 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20850383 | http://www.w3.org/2000/01/rdf-schema#comment | "We enrolled 53 peanut-allergic subjects and 64 peanut-tolerant full siblings, measured peanut-specific IgG and IgE, determined HLA class II at high resolution, and analyzed DRB1 alleles by supertypes. Peanut-specific IgG and IgE were elevated in the peanut-allergic subjects (p<0.0001) but did not stratify with HLA alleles, haplotypes, or supertypes. There were no significant differences in HLA class II between the peanut-allergic and peanut-tolerant siblings but there was an increased frequency of DRB1*0803 in both sets of siblings compared to unrelated controls (p(c)=4.5×10⁻⁹). Furthermore, we identified 14 sibling pairs in which the peanut-allergic and the peanut-tolerant siblings have identical HLA class II and again found an elevation of anti-peanut IgG in the peanut-allergic subjects (p<0.0001). In conclusion, although DRB1*0803 may identify a subset of families with increased risk of peanut allergy, differences in peanut-specific immunoglobulin production between peanut-allergic subjects and their peanut-tolerant siblings are independent of HLA class II."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.clim.2010.08.009"xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Song B."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Wang Q."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Atkins D."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Dreskin S.C."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Aubrey M.T."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Freed B.M."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Talwar H."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Mustafa S.S."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Leo H.L."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Schlichting D."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/author | "Tripputi M.T."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/name | "Clin Immunol"xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/pages | "366-373"xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/title | "Peanut-allergic subjects and their peanut-tolerant siblings have large differences in peanut-specific IgG that are independent of HLA class II."xsd:string |
http://purl.uniprot.org/citations/20850383 | http://purl.uniprot.org/core/volume | "137"xsd:string |
http://purl.uniprot.org/citations/20850383 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20850383 |
http://purl.uniprot.org/citations/20850383 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20850383 |
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-20850383 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20850383 |
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-20850383 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20850383 |
http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-20850383 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20850383 |
http://purl.uniprot.org/uniprot/#_A0A0A0WDZ3-mappedCitation-20850383 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20850383 |