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http://purl.uniprot.org/citations/20850383http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20850383http://www.w3.org/2000/01/rdf-schema#comment"We enrolled 53 peanut-allergic subjects and 64 peanut-tolerant full siblings, measured peanut-specific IgG and IgE, determined HLA class II at high resolution, and analyzed DRB1 alleles by supertypes. Peanut-specific IgG and IgE were elevated in the peanut-allergic subjects (p<0.0001) but did not stratify with HLA alleles, haplotypes, or supertypes. There were no significant differences in HLA class II between the peanut-allergic and peanut-tolerant siblings but there was an increased frequency of DRB1*0803 in both sets of siblings compared to unrelated controls (p(c)=4.5×10⁻⁹). Furthermore, we identified 14 sibling pairs in which the peanut-allergic and the peanut-tolerant siblings have identical HLA class II and again found an elevation of anti-peanut IgG in the peanut-allergic subjects (p<0.0001). In conclusion, although DRB1*0803 may identify a subset of families with increased risk of peanut allergy, differences in peanut-specific immunoglobulin production between peanut-allergic subjects and their peanut-tolerant siblings are independent of HLA class II."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.org/dc/terms/identifier"doi:10.1016/j.clim.2010.08.009"xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Song B."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Wang Q."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Atkins D."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Dreskin S.C."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Aubrey M.T."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Freed B.M."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Talwar H."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Mustafa S.S."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Leo H.L."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Schlichting D."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/author"Tripputi M.T."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/name"Clin Immunol"xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/pages"366-373"xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/title"Peanut-allergic subjects and their peanut-tolerant siblings have large differences in peanut-specific IgG that are independent of HLA class II."xsd:string
http://purl.uniprot.org/citations/20850383http://purl.uniprot.org/core/volume"137"xsd:string
http://purl.uniprot.org/citations/20850383http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20850383
http://purl.uniprot.org/citations/20850383http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20850383
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-20850383http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20850383
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-20850383http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20850383
http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-20850383http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20850383
http://purl.uniprot.org/uniprot/#_A0A0A0WDZ3-mappedCitation-20850383http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20850383