| http://purl.uniprot.org/citations/20881183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20881183 | http://www.w3.org/2000/01/rdf-schema#comment | "The mechanisms of how Th cells promote CD8(+) T cell responses during viral infections are largely unknown. In this study, we unraveled the mechanisms of T cell help for CD8(+) T cell responses during vaccinia virus infection. Our results demonstrate that Th cells promote vaccinia virus-specific CD8(+) T cell responses via two interconnected synergistic pathways: First, CD40L expressed by activated CD4(+) T cells instructs dendritic cells to produce bioactive IL-12p70, which is directly sensed by Ag-specific CD8(+) T cells, resulting in increased IL-2Rα expression. Second, Th cells provide CD8(+) T cells with IL-2, thereby enhancing their survival. Thus, Th cells are at the center of an important communication loop with a central role for IL-2/IL-2R and bioactive IL-12."xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.1001990"xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/author | "Bachmann M.F."xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/author | "Joller N."xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/author | "Crouse J."xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/author | "Oxenius A."xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/author | "Wiesel M."xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/author | "Sporri R."xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/author | "Ehlert A.K."xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/pages | "5188-5197"xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/title | "Th cells act via two synergistic pathways to promote antiviral CD8+ T cell responses."xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://purl.uniprot.org/core/volume | "185"xsd:string |
| http://purl.uniprot.org/citations/20881183 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20881183 |
| http://purl.uniprot.org/citations/20881183 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20881183 |
| http://purl.uniprot.org/uniprot/#_A0A068BD71-mappedCitation-20881183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20881183 |
| http://purl.uniprot.org/uniprot/#_A0A068BER6-mappedCitation-20881183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20881183 |
| http://purl.uniprot.org/uniprot/#_A0A1D8M9B5-mappedCitation-20881183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20881183 |
| http://purl.uniprot.org/uniprot/#_P70443-mappedCitation-20881183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20881183 |
| http://purl.uniprot.org/uniprot/#_A2A5L7-mappedCitation-20881183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20881183 |
| http://purl.uniprot.org/uniprot/#_D3Z6H5-mappedCitation-20881183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20881183 |
| http://purl.uniprot.org/uniprot/#_G3UWR9-mappedCitation-20881183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20881183 |
| http://purl.uniprot.org/uniprot/#_P04227-mappedCitation-20881183 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20881183 |