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http://purl.uniprot.org/citations/20927566http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20927566http://www.w3.org/2000/01/rdf-schema#comment"Gap genes are involved in segment determination during the early development of the fruit fly Drosophila melanogaster as well as in other insects. This review attempts to synthesize the current knowledge of the gap gene network through a comprehensive survey of the experimental literature. I focus on genetic and molecular evidence, which provides us with an almost-complete picture of the regulatory interactions responsible for trunk gap gene expression. I discuss the regulatory mechanisms involved, and highlight the remaining ambiguities and gaps in the evidence. This is followed by a brief discussion of molecular regulatory mechanisms for transcriptional regulation, as well as precision and size-regulation provided by the system. Finally, I discuss evidence on the evolution of gap gene expression from species other than Drosophila. My survey concludes that studies of the gap gene system continue to reveal interesting and important new insights into the role of gene regulatory networks in development and evolution."xsd:string
http://purl.uniprot.org/citations/20927566http://purl.org/dc/terms/identifier"doi:10.1007/s00018-010-0536-y"xsd:string
http://purl.uniprot.org/citations/20927566http://purl.uniprot.org/core/author"Jaeger J."xsd:string
http://purl.uniprot.org/citations/20927566http://purl.uniprot.org/core/date"2011"xsd:gYear
http://purl.uniprot.org/citations/20927566http://purl.uniprot.org/core/name"Cell Mol Life Sci"xsd:string
http://purl.uniprot.org/citations/20927566http://purl.uniprot.org/core/pages"243-274"xsd:string
http://purl.uniprot.org/citations/20927566http://purl.uniprot.org/core/title"The gap gene network."xsd:string
http://purl.uniprot.org/citations/20927566http://purl.uniprot.org/core/volume"68"xsd:string
http://purl.uniprot.org/citations/20927566http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20927566
http://purl.uniprot.org/citations/20927566http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20927566
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